Drug Metabolism as a Community Effort

Drug Target Commons: A Community Effort to Build a Consensus Knowledge Base for Drug-Target Interactions

Knowledge of the full target space of bioactive substances, approved and investigational drugs as well as chemical probes, provides important insights into therapeutic potential and possible adverse effects. The existing compound-target bioactivity data resources are often incomparable due to non-standardized and heterogeneous assay types and variability in endpoint measurements. To extract hig...

JHB as a Collaborative Effort.

Chiral drug metabolism: a perspective.

456 biggest problems is in understanding the fundamental mechanisms involved and predicting the CSP to be used for specific problems. Although Pirkle phases and cyclodextrin phases offer the best rationale for use, in general most decisions are based on empirical experiments, with a degree of justification post fact0 in terms of the proposed mechanism involved. The protein columns based on AGP ...

The Open Graph Archive: A Community-Driven Effort

In order to evaluate, compare, and tune graph algorithms, experiments on well designed benchmark sets have to be performed. Together with the goal of reproducibility of experimental results, this creates a demand for a public archive to gather and store graph instances. Such an archive would ideally allow annotation of instances or sets of graphs with additional information like graph propertie...

Measuring progress of collaborative action in a community health effort.

OBJECTIVE To measure the progress made by the collaborative actions of multisectorial partners in a community health effort using a systematic method to document and evaluate community/system changes over time. METHODS This was a community-based participatory research project engaging community partners of the Latino Health for All Coalition, which based on the Health for All model, addresses...